Limited access

Upgrade to access all content for this subject

Viruses have one main objective: to replicate. However, when viruses infect higher organisms such as humans, the job of host's immune system is to eliminate any possible pathogens. This creates an arms race between the host and the pathogen. Viruses have evolved many techniques to evade host immune responses. One of these immunoevasion techniques employed by herpes viruses is to produce a protein, ICP47, which blocks the TAP transporter protein.

What effects does this have in a herpes infected cell?​

A

$\beta_2$-microglobulin does not assemble with the MHC Class I molecule.

B

Peptides are not loaded into MHC Class I molecules.

C

Peptides are not loaded into MHC Class II molecules.

D

MHC Class II molecules do not migrate to the cell surface.

Select an assignment template