Limited access

Upgrade to access all content for this subject

The presentation of antigens in the context of MHC does not discriminate between self and non-self antigens. Nevertheless, the immune system exhibits noticeable responses against non-self antigens but usually not against self antigens.

T cells only respond to foreign antigens because


T cells only recognize antigens in the context of the environment.


T cells only ingest and process unknown unfamiliar antigens.


T cells are always killed if they recognize self antigens in the context of self MHC (i.e., removed through apoptosis).


T cells are programmed to recognize differences between the same antigen derived from different self or foreign sources.

Select an assignment template