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The ‘heterozygote advantage’ refers to the observation that people with the most diverse MHC haplotypes are more protected against infectious disease.

How would the “heterozygote advantage” affect allograft rejection rates?

A

Decreased incidence of hyperacute rejection rates.

B

Increased incidence of acute rejection.

C

Decreased incidence of acute rejection.

D

No impact – someone with heterozygote advantage would have the same incidence of rejection as someone with less heterozygosity.

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