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The ‘heterozygote advantage’ refers to the observation that people with the most diverse MHC haplotypes are more protected against infectious disease.

How would the “heterozygote advantage” affect allograft rejection rates?


Decreased incidence of hyperacute rejection rates.


Increased incidence of acute rejection.


Decreased incidence of acute rejection.


No impact – someone with heterozygote advantage would have the same incidence of rejection as someone with less heterozygosity.

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