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Figure 1 shows a diagram of the major determinants of gastric acid secretion in the stomach. ECL = enterochromaffine-like, G = gastrin, H = histamine, H+ = protons, H2 = histamine receptor in gastric mucosa , ST2 = somatostatin receptor; “+” indicates a stimulatory response, “-“ indicates an inhibitory response. “Gastric acid.” Wikipedia: The Free Encyclopedia. Wikimedia Foundation, Inc., 16 Sept. 2016. Web. 19 Sept. 2016.

Given Figure 1, blocking histamine receptors with an antagonist will have what effect?


Less gastrin will be released by G cells.


More somatostatin will be released by D cells.


Less acid will be released by parietal cells.


Less histamine will be released by ECL cells.

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