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A student is spending the summer working with mice in a lab and wishes to understand the mechanisms governing the development of trisomy conditions, particularly trisomy 21, or Down syndrome. In Down syndrome, affected individuals contain an extra copy of chromosome 21.

What experimental intervention is MOST similar to the biological processes governing the development of Down syndrome?

A

Cutting of the microtubules on one half of the cell with a high powered laser during meiosis I.

B

Exposure of oocytes to ionizing radiation.

C

Exposure of the oocytes to alkylating agents such as cyclophosphamide.

D

In vitro fertilization under high salt conditions.

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