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From the options below, select the true instances of cell death being part of normal development of the nervous system.

Select ALL that apply.

A

Elimination of excess motor neurons that failed to establish appropriate connections with muscle cells and thus became deprived of muscle-derived cell survival factors.

B

Elimination of excess of oligodendrocytes that failed to myelinate a nerve fiber and thus became deprived of axon-derived cell survival factors.

C

Degeneration of cerebellar Purkinje neurons that express the mutant form of the ATXN1 gene.

D

Stereotypical cell death observed in the proliferative areas of the developing human telencephalon, ventricular zone, and later subventricular zone, around mid-gestation.

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