Neural crest cells (NCCs) are specified during neurulation at the border of the neural plate and non-neural ectoderm. Upon neural tube closure, NCCs residing in the roof plate undergo epithelial-to-mesenchemal transition (EMT).
During EMT, NCCs delaminate from the roof plate and migrate throughout the developing embryo giving rise to various cell types and tissues.
Which of the following diseases are related to abnormal neural crest development?
Select ALL that apply.