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The way the peripheral and central nervous system response and repair injuries to tissue and neurons is different and a great focus of research.

What is the primary and most important difference in the way the peripheral and central nervous systems respond and repair injuries?


Sensory information is lost in PNS injury and not in CNS injury.


The PNS can repair axons and regain connections that were lost. The CNS cannot repair axons easily and connections are rarely regained.


Only CNS neurons experience Wallerian degeneration, the dying back of injured axons.


Neurotrophic factors, which promote axon regrowth, are only present during PNS injury and not CNS.

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