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The blood-brain barrier (BBB) is an important component of protection for the brain.

Which of the following is a property of the BBB? Select ALL that apply.

A

It is generally permeable to lipid-soluble compounds.

B

It is absent in portions of the hypothalamus.

C

Astrocytes surround the CNS capillaries.

D

The capillary endothelial cells are interconnected by tight junctions.

E

It is generally permeable to protein compounds.

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