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Bensaccount. File:G-protein-coupled Receptor.png. Digital image. Wiki Commons, 29 Apr. 2006. Web. 24 Apr. 2016.

Webb, Isaac. "Ion Channel Receptor." Ion Channel Receptor. Wiki Commons, 23 May 2014. Web. 24 Apr. 2016.

The postsynaptic membrane receptors are typically either ionotropic receptors or metabotropic receptors. The receptors within the diffuse modulatory systems are generally G-coupled receptors.

The G-coupled receptors (metabotropic) are different from the ionotropic receptors, such as ligand-gated​ ion channels.

Which of the following statements explains a difference between ligand-gated ion channels and G-coupled receptors?


A ligand activates the receptor.


Ligand activation triggers the opening of an ion channel.


Protein activation triggers the ​release of an intracellular secondary messenger.


A neurotransmitter binds to the receptor to trigger a post-synaptic response.

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