In many instances, the number of axons innervating a given cell is dramatically reduced during neuronal circuit maturation. For example, early in the postnatal period, a single neuron in the lateral geniculate nucleus of the thalamus (LGN) receives inputs from over 20 retinal ganglion cells (RGC). In the following three weeks of visual system development, the number of inputs drops to just one to three. However, synaptic drive, the response of LGN neurons to RGC activity, increases.
Which of the following could account for this seemingly counterintuitive phenomenon?
Select ALL that apply.